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Process principles
Wet granulation (high shear granulation/high shear mixing) in a vertical or top-drive granulator is the classical method
for building up granulates from powder.
(->
Wet Granulation)
In this process, powder is fed to a product container and then
moistened or sprayed with molten material in order to increase
the cohesive
forces. The liquid can be water or an organic solvent, if necessary
with a binder. At the same time, the ingredients are mixed together
vigorously.
Denser granulates are formed than in the case of Agglomeration/Granulation
in the fluid bed.
Product characteristics
Wet granulate |
- Dust free
- Good flow behaviour
- Easy to dose
- Good dispersibility
- Good solubility
- Highly suitable for making into tablets
- Compact structure
- Low hygroscopicity
- High bulk density
- Wide grain size distribution
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Manufacturing options
For this process, Glatt offers Vertical
Granulators with batch sizes from 100g to 1t/batch.
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