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Process principles
In solid processes, various individual products of different density
and concentration and in different amounts are often admixed to
form a homogeneous mixture. (
-> Container Blending)
In the pharmaceutical area, very different quantities and proportions
of active and auxiliary ingredients (corn starch, lactose, PVP,
etc.) are mixed together.
Specific auxilliary materials such as lubricants or flavourings
may also be added.
Mixing may be necessary in different process sections. For instance,
compression aids, flow controlling media and external phases are
added following the granulation process and before compression.
Requirements for the blending process
- Defined mixing proportions
- Dust free
- Reproducible
- Long shelf life
- Homogeneous
Different blending options
For this process, Glatt offers drum and container blenders for
container sizes from 10l to 3000l/batch.
Blending processes can also be carried out before the process step
Agglomeration/Granulation
directly in the vertical granulator or in the fluid bed system.
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