TYAML - Yet Another Multicolumn Layout for TYPO3

High shear granulation

The solution for especially compact granulate

High shear granulation is a shaping process for granulation that has been enhanced for application in the pharmaceutical industry. A binder liquid is fed to the powder particles in a closed container with blending tools and a chopper. Dense granules are formed through the liquid and solid bridges that result. For optimal handling and further processing of a product.

High shear granulation in a closed container with blending tools driven from above or below has long been applied by the pharmaceutical industry. The mechanical effect of the blending tools – irrespective of whether in batches or continuous operation – creates a denser granulate than the fluidized bed process.

Originally, the granulation liquid was poured into the product. Today, an improved dosed distribution using a spray nozzle is preferred in order to obtain a more even granulate.

The granules are distinguished by a compact structure and high bulk density. They have good flow characteristics and can be optimally pressed. For various applications in pharmaceuticals and related industries.

Video: High Shear Granulation

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