The practice-proven MODCOS (Modular Continuous System) offers the optimal solution for modular and flexible continuous production processes.
With the Modular Continuous System (MODCOS), Glatt offers a flexible production system for the continuous manufacture of coated tablets – from product development to commercial production. The modular, multi-purpose system can be adapted precisely to the respective requirements, enabling short development times, rapid scaling, and maximum process reliability.
The system covers the entire process chain:
from precise excipient and API dosing to wet granulation and drying to tableting and tablet coating. All unit operations are seamlessly integrated into the central GlattView CONTI system control. Consistent product quality is controlled by Process Analytical Technology (PAT) or continuously monitored and controlled by closed control loops.
Thanks to fully automated, recipe-controlled processes, the process remains traceable at all times through track & trace functionality. At the same time, the modular system architecture enables fast product and batch changes – ideal for dynamic production environments.
The MODCOS xs-, s-, and m-line systems are specially designed for continuous wet granulation with subsequent drying. They are ideal for formulation development and initial feasibility studies – from powder to reproducible granules. The systems can be controlled manually, allowing process parameters to be tested flexibly and defined precisely.
Thanks to consistent scale-up strategies, the process parameters evaluated during the development phase can be seamlessly transferred to MODCOS production lines. Individually configurable process modules enable targeted adaptation to formulation requirements and production goals – from research and development to commercial manufacturing.
Minimal conversion effort, maximum economic benefit
Within the framework of the MODCOS concept, existing batch granulators from the GPCG series can be efficiently integrated into a continuous process chain.
This modular integration concept significantly reduces investment costs and opens up the possibility of gradually transitioning to continuous technology—without replacing existing equipment.
MODCOS offers flexible and customized solutions for continuous direct compaction. The various powder components are fed continuously and with high precision via gravimetric multi-ingredient dosing. The system automatically adjusts its hold-up to the respective throughput, ensuring that residence times remain stable and the process is optimally controlled.
Thanks to loss-in-weight dosing technology, the solid material flows are reliably controlled. In combination with Process Analytical Technology (PAT), the amount of material fed remains constant – process stability and reproducibility of product quality are guaranteed at all times.
The integration of downstream process steps such as tableting or capsule filling is carried out directly by Glatt in accordance with customer specifications. This creates a fully connected, continuous production line – from raw material dosing to the finished product.
Performance range: from 5 kg/h to 1,000 kg/h, scalable to individual production requirements.
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