Career
Contact
You are here: / / Fluidized bed systems

Fluidized bed systems

Glatt and fluidized bed technology

As a pioneer in fluidized bed technology, we offer our customers a wide range of fluid bed systems for all powder processing industries. From laboratory and pilot plants to complex systems for production.

Whether in batch or continuous operation, anything is possible with fluid bed systems from Glatt: Our laboratory systems are capable of processing product quantities as small as a few grams – the capacities of our production systems can reach several tons.

Discover our various fluidized bed systems for your individual requirements!

Laboratory and pilot equipment

Do you want to experiment with new formulations? Or do you need to test various processing options in the fluidized bed? Our multi-functional lab and pilot systems for fluid bed processing have proven themselves many times in process development and in reliably transferring from a laboratory to a production scale. The modular structure and flexible configuration make it possible to respond quickly and effectively to changing demands.

Icon

Fluidized bed lab units (PDF)

1 file(s) 8 MB
Download

Icon

Pilot system GPCG 10 (PDF)

1 file(s) 3 MB
Download

Icon

Functionalization of Granules & Pellets (PDF)

1 file(s) 1 MB
Download

Icon

ProCell LabSystem (PDF)

1 file(s) 1 MB
Download

Mini-Glatt / Midi-Glatt

The Mini-Glatt and Midi‑Glatt are our bestsellers for all batch fluid bed processes for testing granulation, drying, and coating processes. Ideal for minimum batch sizes from 5 to 1,850 grams. Processes in bottom and top spray are possible. Versatile retrofit options available as needed.

GPCG.Lab

MultiLab® GPCG.Lab process module with granulation, drying and coating process options in trusted Glatt quality.
Multiple process combinations with just 6 process combi containers in 3 l, 6 l and 10 l.

GPCG 10

The GPCG 10 is our modular all-rounder for all batch fluid bed processes and demanding scale-up on a pilot scale: from simple drying through granulation or agglomeration to coating and pelletizing. No matter whether top spray, bottom spray or tangential spray – whether Wurster coating or production of micropellets with the patented CPS process. A flexible all-rounder for your individual needs. Ideal for batch sizes from 2 kg to 25 kg.

ProCell® LabSystem

Our all-rounder system for maximum flexibility on a laboratory scale: Modular process inserts allow top spray, bottom spray and Wurster coating for fluid bed, spouted bed or rotor processes in continuous or batch operation. Whether it is spray granulation or encapsulation of liquids, agglomeration of powders, powder coating or coating of particles: Everything is possible.

Details of the ProCell® LabSystem.

ProCell® PilotSystem

Our modular pilot plant for process development, process optimization and scale-up in continuous operation. Different process inserts allow top spray and bottom spray for fluid bed or spouted bed processes. Whether it is spray granulation of liquids, agglomeration of powders, coating of particles or encapsulation of liquids. Design your process the way you need it.

Details of the ProCell® PilotSystem at the Glatt Technology Center Weimar.

AGT® PilotSystem

Our modular pilot plant for process development, process optimization and scale-up in continuous and batch operation. Different process inserts for maximum process flexibility allow top spray and bottom spray for fluid bed or rotor processes. Whether it is spray granulation of liquids, agglomeration of powders, powder coating, Wurster coating or encapsulation of liquids: Everything is possible.

Details of the AGT® PilotSystem at the Glatt Technology Center Weimar.

Production plants

We offer a wide range of high-performing mass production technology systems for your fluidized bed processing in batch or continuous production mode. Our modular system concepts permit varied processing options. Just the way you need it.

Icon

Fluidized bed production plants (PDF)

1 file(s) 8 MB
Download

Icon

Functionalization of Granules & Pellets (PDF)

1 file(s) 1 MB
Download

Icon

TwinPro® (PDF)

1 file(s) 919 kB
Download

Icon

Glatt GF ModFlex (PDF)

1 file(s) 196 kB
Download

WSG PRO

The WSG PRO is our well-established fluid bed talent WSG PRO, for granulation of solids in the top spray process with uniform, consistent quality. High process efficiency due to extremely fast drying with gentle product handling. For batch sizes from 5 to 1,500 kilograms per batch. Other batch sizes on request.

GPCG PRO

Our multi-talent GPCG PRO for all fluid bed processes with maximum flexibility: from simple drying and granulation to pelletizing and sophisticated particle coating. For homogeneously shaped products in consistent quality. No matter if top spray, bottom spray or tangential spray – everything is possible. Batch sizes from 5 to 1,500 kilograms per batch. Other batch sizes on request. By using appropriate modules, continuous processes are also possible in addition to batch operation.

TwinPro®

The TwinPro® system combines high shear granulation and fluidized bed drying in a single process.

For the first time, the revolutionary, patent pending TwinPro® system unites two previously separate processes, high shear granulation and fluid bed drying, in a continual batch process.

The revolutionary fusion of two processes into a single system allows the company to remove a complete machine unit, reducing investment costs in systems and building technology with maximum process efficiency.

AGT®

Our fluid bed performers AGT® for efficient granulation drying: round single-chamber production plants for continuous spray granulation of liquids. The equipment enables drying of liquid raw materials with simultaneous build-up of granules in an optimally mixed fluidized bed. Gentle treatment of temperature-sensitive materials. Direct granulation of highly viscous liquids is also possible.

Further information on the AGT® series.

AGT® System

Our all-rounder AGT® System for maximum process flexibility: round production systems with exchangeable process chamber for all fluid bed, spouted bed, and rotor processes. Whether spray granulation of liquids or agglomeration of powders, whether coating and powder layering of particles or encapsulation of liquids – everything is possible. In continuous or batch-controlled operation. Tailored to your process.

Further information on the AGT® series.

GF

Our fluid bed multi-purpose equipment GF for a wide range of process combinations: rectangular multi-chamber production systems for combining all continuous fluid bed processes. Whether spray granulation or encapsulation of liquids, agglomeration of powders or coating of particles – the plug flow through the process chambers allows a combination of the processes as well as the subsequent drying and cooling. Exactly the way you need it.

Further information on the GF series.

GF ModFlex

Our fluid bed system in modular compact design with integrated room and zone concept. The modular, Atex-compliant system solution with integrated WIP system and plate filter concept allows continuous spray agglomeration – including in rooms with limited building heights. Among other things, the low operating costs ensure cost-effectiveness, as the energy-optimized unit does not require additional air conditioning. Commissioning after an installation period of only 12 days is feasible because defined modules are already pre-assembled. They are simply connected on site and production can start after the acceptance test.

Further information on the GF series.

GF ModFlex

Modular, Atex-compliant system solution for continuous spray agglomeration.

Spray systems

Granulating, coating and pelletizing – with the unique Glatt nozzles

The Glatt LD Top spray nozzle is ideal for granulation and coating processes. Its clever and lightweight design guarantees optimum spray rates, prevents clogging, guarantees easy handling and very good cleanability. It is also extremely robust. It works according to the binary principle and can therefore be ideally adjusted for any granulation process. Equipped with SmartID for smart verification of critical process components.

The patented Glatt HS method is used for coating processes in the Wurster (bottom spray). The HS Wurster spray nozzle guarantees very high spray rates and enables the coating of even micro-fine particles (>50 μm).

With direct pelletizing, coating in the rotor and the High-Performance (HP) spray system, the nozzle sprays laterally directly into the product bed. With powder layering, a special 3-component nozzle which precisely meters the powder together with the spraying liquid, ensures precise layering.

Icon

Top Spray Nozzle (PDF)

1 file(s) 163 kB
Download

Filter systems

Glatt offers a wide range of filter options: Systems with single or double chamber principle, vibrating or blow-out filters, filter socks or filter cartridges, textile or metal filters: Each system has its specific advantages and is recommended and offered by Glatt for very specific products and processes.

Patented lowerable metal filter

Our SC SuperClean® filters allow fully automatic filter cleaning on site. Unlike other cleanable filters available on the market to date, our patented blow-out SC SuperClean® filters are mechanically extremely stable and practically wear-free, enable faster system maintenance and are particularly user-friendly thanks to the lowerable filter plate. They have excellent filtration properties with a long lifespan.

The entire cleaning concept is suitable for CIP and containment: it enables an automatic, efficient, validatable cleaning process in the closed system.

Icon

Filter Systems (p. 21) (PDF)

1 file(s) 3 MB
Download

CPS™ technology

The Glatt CPS™ technology (Complex Perfect Spheres Technology) is a further development of the rotor fluidized bed process. It makes it possible to manufacture functionalized pellets and micropellets with perfect roundness and surface. Direct pelletizing allows for a variety of drug formulations to be realized in extremely low or very high doses.

Unlike traditional rotor systems, the CPS ™ technology works with a conically tilted rotating disc that allows for a directional particle motion. It is possible to clearly define the end point of the pelletization.

No starter pellets are required for direct pelletizing with the Glatt CPS ™ technology. The concentrations of the active ingredients in the pellet matrix can vary from less than 0.1 percent up to a drug load of 90 percent. Round and evenly shaped pellets are achieved, with precisely defined pellet sizes between 100 and 1,500 micrometers with an extremely narrow size distribution.

Microcrystalline cellulose is often used as an important excipient. The pellet matrix can contain other pharmaceutical excipients, such as polymers, and disintegrating or solubilizing agents.

CPS™ pellets and micropellets are especially suitable as carrier cores for coating applications for an optimized active ingredient release or for taste masking. Optimally defined film qualities can be achieved.

Our innovative solution for your formulation.

MicroPx™ technology

The Glatt MicroPx™ technology (micro pelletizing technology) is a continuous fluidized bed agglomeration process for the manufacture of pellets and micropellets with a very high active ingredient content. Functional excipients – for example to control the release of the active ingredient or to optimize bioavailability – can be integrated into the pellet matrix.

Unlike the traditional Wurster fluidized bed process, in which starter cores or pellets are coated with the active substance or functional coats, the MicroPx™ technology works without a product template. This new technology allows the manufacturing of micropellets in sizes ranging from 100 to 400 micrometers with very narrow particle size distribution and consistent active ingredients contents of 90 to 95 percent.
Pharmaceutical substances together with the excipients are sprayed in liquid form into the MicroPx™ fluidized bed system. Initial spray drying creates product dust at first, which is agglomerated in a controlled manner in the starting phase of the process. Subsequently, these primary particles are built up to micropellets in layers until they reach the desired size.
A fundamental component of the MicroPx™ technology is a classifying zig-zag sorting function. Micropellets of proper size are continuously discharged from the process via air separation, while particles that are still too small are returned to the processing chamber where they are built up further.

The MicroPx™ technology is the perfect procedure to obtain micropellets for subsequent coating for taste masking.

Our intelligent solution for your drugs.